Cap Assembly for a Medicament Delivery Device

ABSTRACT

A cap assembly for a medicament delivery device is disclosed. The cap assembly includes a cap configured to be mounted to a proximal end of the medicament delivery device, wherein the cap comprises a cam surface. The cap assembly further includes a squeezer comprising (i) a body defining a first longitudinally extending channel configured to receive a delivery member shield and (ii) a plurality of radial arms flexible in a radial direction. The cap assembly also includes a spinner comprising (i) a proximal end face configured to cooperate with the cam surface of the cap, (ii) a body defining a second longitudinally extending channel configured to receive the squeezer, and (iii) a plurality of holes in the body of the spinner configured to receive the plurality of radial arms of the squeezer.

The present application is a continuation of U.S. patent applicationSer. No. 15/583,467, filed on May 1, 2017 entitled “Cap Assembly for aMedicament Delivery Device,” which is incorporated entirely herein byreference as if fully set forth in this description.

TECHNICAL FIELD

The present disclosure generally relates to medical devices. Inparticular, it relates to a cap assembly for a medicament deliverydevice, to a medicament delivery device comprising such a cap assembly,and to a method of assembling a sub-assembly for a medicament deliverydevice.

BACKGROUND

Medicament delivery devices, such as injectors and inhalers, typicallycomprise a housing in which a medicament container containing amedicament is to be arranged. Upon activation of the medicament deliverydevice, the medicament is expelled through a medicament delivery member,for example a needle or a nozzle.

In order to protect and to keep the medicament delivery member sterile,the medicament delivery member may be provided with a delivery membershield, or sheath, such as a Flexible Needle Shield (FNS) or a RigidNeedle Shield (RNS). The delivery member shield may thus be attached tothe medicament container to cover the medicament delivery member, duringassembly of the medicament container or of the medicament deliverydevice.

Moreover, the medicament delivery device may comprise a removable capwhich is mounted to the proximal end of the housing, i.e. that end whichis placed towards the injection site during medicament delivery, of themedicament delivery device, or to the proximal end of the medicamentcontainer. The removable cap has the function of providing mechanicalprotection of the medicament delivery member while attached to thehousing or medicament container, and to remove the delivery membershield when the cap is removed from the housing.

WO2015110532 A1 discloses an auto-injector having a connector forconnecting a needle cover to a removable cap. The connector has aplurality of legs spaced symmetrically away from one another about acentral hub. The legs have an elastic nature and aid in securing theneedle cover and/or rigid needle shield to a cap insert and hence to theremovable cap. The needle cover and/or needle shield are securedtogether through upper, internally facing barbs protruding from thefirst legs. The upper, internally facing barbs include tips that pointtoward the forward end of the connector. These barbs are shaped toengage the needle cover and/or rigid needle shield when the needle coverand/or rigid needle shield is fitted within the connector. The barb tipsapply opposing force with respect to one another when they engage theneedle cover and/or rigid needle shield when the needle cover and/orrigid needle shield is fitted within the connector.

SUMMARY

According to the design disclosed in WO2015110532 A1, the legs of theconnector are flexed towards each other as soon as the connector isplaced in the cap insert. This bending of the legs renders it moredifficult to insert the needle cover/rigid needle shield into theconnector, thereby making assembly more difficult.

In view of the above, a general object of the present disclosure is toprovide a cap assembly for a medicament delivery device which solves orat least mitigates the problems of the prior art.

There is hence according to a first aspect of the present disclosureprovided a cap assembly for a medicament delivery device, comprising: acap having a tubular body defining an axially extending distal openingand configured to be mounted to a proximal end of a medicament deliverydevice, wherein the cap has a bottom structure defining a proximal endof the distal opening, wherein the bottom structure has a cam structureprovided inside the tubular body, and wherein the tubular body has innerwalls provided with radial recesses extending in the longitudinaldirection along the inner walls, and an elongated squeeze memberconfigured to be received in the distal opening of the tubular body, andhaving a longitudinally extending channel configured to receive adelivery member shield, and which squeeze member has radial armsflexible in the radial direction and forming part of a wall of thechannel, wherein the squeeze member has a proximal end face configuredto cooperate with the cam structure of the cap, whereby axialdisplacement of the squeeze member from a first position in which theproximal end face bears against the cam structure to a second positionin which the squeeze member is received further by the cap causesrotation of the squeeze member relative to the cap, wherein the radialarms are configured to engage with a respective radial recess of thetubular body in the first position of the squeeze member, and whereinthe radial arms are configured to disengage from the respective radialrecess when the squeeze member is displaced from the first position tothe second position and rotated, whereby the flexible radial arms arepressed into the channel by the inner walls of the tubular body,reducing a cross-sectional area of the channel.

The squeeze member is thus able to provide radial pressure on, orsqueeze, a delivery member shield when a delivery member shield isinserted into the channel of the squeeze member and the squeeze memberis moved proximally inside the distal opening of the cap, to the secondposition. The cap may hence in a simple manner be mounted to thedelivery member shield, and removed from a medicament container when thecap assembly is removed from a medicament delivery device.

According to one embodiment the cam structure is annular in a radialplane and comprises a plurality of elevated portions with a cut-outhaving oppositely inclined surfaces provided between each adjacent pairof elevated portions, in the circumferential direction of the camstructure.

According to one embodiment the proximal end face of the squeeze membercomprises a plurality of elevated portion with a cut-out havingoppositely inclined surfaces provided between each adjacent pair ofelevated portions of the proximal end face, in the circumferentialdirection of the squeeze member.

According to one embodiment each elevated portion of the squeeze memberis configured to bear against a region of a cut-out of the cam structurecloser to an elevated portion of the cam structure than to a lowestelevational point of the cut-out, in the first position of the squeezemember.

According to one embodiment the elevated portions of the squeeze memberare configured to engage with the cut-outs of the cam structure in thesecond position of the squeeze member.

According to one embodiment at least two of the radial arms are arrangedopposite to each other in a radial plane of the squeeze member, causingthe two radial arms to move towards each other in the second position ofthe squeeze member.

According to one embodiment two of the radial arms are arranged in afirst radial plane of the squeeze member, and wherein two other radialarms are arranged in a second radial plane axially spaced apart from thefirst radial plane.

According to one embodiment the two radial arms arranged in the firstplane are arranged 90 degrees offset in the circumferential directionrelative to the two arms arranged in the second plane.

According to one embodiment the radial recesses have inclined surfacesin the circumferential direction allowing the radial arms to disengagewhen the squeeze member is rotated while displaced from the firstposition to the second position.

According to one embodiment the radial arms have an increasing thicknessin a direction from their point of attachment towards their endportions, wherein the thickness of each end portion is thicker than awall thickness of the channel.

According to one embodiment the radial recesses extend in thelongitudinal direction along a majority of the length of the inner wallsof the tubular body.

There is according to a second aspect of the present disclosure provideda medicament delivery device comprising: a body having a proximalopening, and a cap assembly according to the first aspect, wherein thecap assembly is configured to be mounted to the medicament deliverydevice to cover the proximal opening of the body.

One embodiment comprises a surface configured to bear against a distalend face of the squeeze member.

There is according to a third aspect provided a method of assembling asub-assembly for a medicament delivery device, comprising: a) providinga cap assembly according to the first aspect, b) inserting the squeezemember into the distal opening of the cap and moving the squeeze membertowards the bottom structure until the proximal end face of the squeezemember contacts the cam structure to obtain the first position of thesqueeze member, and c) assembling the cap with the squeeze memberarranged therein with a medicament container assembly comprising adelivery member shield, such that the squeeze member receives thedelivery member shield.

According to one embodiment step c) includes moving a distal end face ofthe squeeze member towards a proximal surface of the medicamentcontainer assembly, causing the squeeze member to move proximally insidethe cap from the first position to the second position causing theradial arms to squeeze the delivery member shield.

According to one embodiment the delivery member shield is a rigid needleshield or a flexible needle shield.

There is according a fourth aspect of the present disclosure a capassembly for a medicament delivery device. In an example embodiment ofthis aspect, the cap assembly includes a cap configured to be mounted toa proximal end of the medicament delivery device, wherein the capcomprises a cam surface. The cap assembly further includes a squeezercomprising (i) a body defining a first longitudinally extending channelconfigured to receive a delivery member shield and (ii) a plurality ofradial arms flexible in a radial direction. Still further, the capassembly includes a spinner comprising (i) a proximal end faceconfigured to cooperate with the cam surface of the cap, (ii) a bodydefining a second longitudinally extending channel configured to receivethe squeezer, and (iii) a plurality of holes in the body of the spinnerconfigured to receive the plurality of radial arms of the squeezer.Axial displacement of the spinner from (i) a first position in which theproximal end face bears against the cam surface and each radial arm ofthe plurality of radial arms is positioned in a respective hole of theplurality of holes to (ii) a second position in which the spinner isreceived further by the cap causes rotation of the spinner relative tothe cap and the squeezer. Further, rotation of the spinner relative tothe cap and the squeezer causes the body of the spinner to force eachradial arm out of the respective hole and into the first longitudinallyextending channel, so as to reduce a cross-sectional area of the firstlongitudinally extending channel.

There is according a fifth aspect of the present disclosure a medicamentdelivery device. In an example embodiment of this aspect, the medicamentdelivery device includes a body having a proximal opening and a capassembly such as the cap assembly according to the fourth aspect. Thecap assembly is configured to be mounted to the medicament deliverydevice to cover the proximal opening of the body.

There is according a sixth aspect of the present disclosure a capassembly for a medicament delivery device. In an example embodiment ofthis aspect, the cap assembly includes a cap configured to be mounted toa proximal end of the medicament delivery device, wherein the capcomprises a cam surface. The cap assembly further includes a squeezercomprising (i) a body defining a first longitudinally extending channelconfigured to receive a delivery member shield and (ii) a plurality ofradial arms flexible in a radial direction. Still further, the capassembly includes a spinner comprising (i) a proximal end faceconfigured to cooperate with the cam surface of the cap, (ii) a bodydefining a second longitudinally extending channel configured to receivethe squeezer, and (iii) a plurality of holes in the body of the spinnerconfigured to receive the plurality of radial arms of the squeezer. Yetstill further, the cap assembly includes a clamp axially fixed to adistal end of the squeezer, wherein the clamp comprises a plurality ofclamp arms flexible in a radial direction from an open position to aclosed position. Axial displacement of the spinner from (i) a firstposition in which the proximal end face bears against the cam surfaceand each radial arm of the plurality of radial arms is positioned in arespective hole of the plurality of holes to (ii) a second position inwhich the spinner is received further by the cap causes rotation of thespinner relative to the cap and the squeezer. Rotation of the spinnerrelative to the cap and the squeezer causes the body of the spinner toforce each radial arm out of the respective hole and into the firstlongitudinally extending channel, so as to reduce a cross-sectional areaof the first longitudinally extending channel.

There is according a seventh aspect of the present disclosure a methodof assembling a sub-assembly for a medicament delivery device. In anexample embodiment of this aspect, the method includes providing a capassembly such as the cap assembly of the sixth aspect. The methodfurther includes inserting the squeezer into the second longitudinallyextending channel of the spinner and inserting the spinner into the capin a proximal direction and moving the spinner until the proximal endface of the spinner contacts the cam surface to obtain the firstposition of the spinner. Still further, the method includes assemblingthe cap with the spinner and squeezer arranged therein with a medicamentcontainer assembly comprising a delivery member shield and a syringe,such that the squeezer grips the delivery member shield and the clampgrips a neck of the syringe.

Generally, all terms used in the claims are to be interpreted accordingto their ordinary meaning in the technical field, unless explicitlydefined otherwise herein. All references to “a/an/the element,apparatus, component, means, etc. are to be interpreted openly asreferring to at least one instance of the element, apparatus, component,means, etc., unless explicitly stated otherwise.

BRIEF DESCRIPTION OF THE DRAWINGS

The specific embodiments of the inventive concept will now be described,by way of example, with reference to the accompanying drawings, inwhich:

FIG. 1 is a perspective view of an example of a medicament deliverydevice without an activation assembly;

FIG. 2 shows an exploded view of the medicament delivery device in FIG.1;

FIG. 3 shows an example of a cap assembly;

FIG. 4 is a top view of a cap;

FIG. 5 is a longitudinal section of the cap in FIG. 4;

FIG. 6 shows the squeeze member arranged in the cap in a first positionof the squeeze member;

FIG. 7 is a top view of the cap assembly shown in FIG. 6;

FIG. 8 is a longitudinal section of the squeeze member arranged in thecap in a second position of the squeeze member;

FIG. 9 is a top view of the cap assembly shown in FIG. 8;

FIG. 10 shows a perspective view of an example of a medicament containerassembly;

FIG. 11 shows a longitudinal section of a proximal portion of anelongated body of the medicament container assembly;

FIG. 12 shows a longitudinal section of a sub-assembly comprising thecap assembly and the medicament container assembly during assembly;

FIG. 13 shows a longitudinal section of the sub-assembly in FIG. 12 whenthe cap assembly and the medicament container assembly have beenassembled;

FIG. 14 is a flowchart showing a method of assembling a sub-assemblyincluding the cap assembly and the medicament container assembly;

FIG. 15 is a flowchart showing a method of assembling a sub-assemblyincluding the cap assembly and the medicament container assembly;

FIG. 16 illustrates a perspective view of an example medicament deliverydevice without an activation assembly, according to an exampleembodiment of the present disclosure;

FIG. 17 illustrates an exploded view of the example medicament deliverydevice of FIG. 16, according to an example embodiment of the presentdisclosure;

FIG. 18 illustrates a perspective view of an example cap of the examplemedicament delivery device of FIG. 16, according to an exampleembodiment of the present disclosure;

FIG. 19 illustrates a perspective view of an example squeezer of theexample medicament delivery device of FIG. 16, according to an exampleembodiment of the present disclosure;

FIG. 20 illustrates a perspective view of an example spinner of theexample medicament delivery device of FIG. 16, according to an exampleembodiment of the present disclosure;

FIG. 21 illustrates a perspective view of a proximal end of the examplemedicament delivery device of FIG. 16 in an initial state, according toan example embodiment of the present disclosure;

FIG. 22 illustrates a perspective view of a proximal end of the examplemedicament delivery device of FIG. 16 in an assembled state, accordingto an example embodiment of the present disclosure;

FIG. 23 illustrates a top view of a proximal end of the examplemedicament delivery device of FIG. 16 in an initial state, according toan example embodiment of the present disclosure;

FIG. 24 illustrates a top view of a proximal end of the examplemedicament delivery device of FIG. 16 in an assembled state, accordingto an example embodiment of the present disclosure;

FIG. 25 illustrates a perspective and partial cross-sectional view ofthe example medicament delivery device of FIG. 16 in an initial state,according to an example embodiment of the present disclosure;

FIG. 26 illustrates a perspective and partial cross-sectional view ofthe example medicament delivery device of FIG. 16 in an assembled state,according to an example embodiment of the present disclosure;

FIG. 27 illustrates a side view of a proximal end of the examplemedicament delivery device of FIG. 16 in an initial state, according toan example embodiment of the present disclosure;

FIG. 28 illustrates a side view of a proximal end of the examplemedicament delivery device of FIG. 16 in an assembled state, accordingto an example embodiment of the present disclosure; and

FIG. 29 illustrates an example method, according to an exampleembodiment of the present disclosure.

DETAILED DESCRIPTION

The inventive concept will now be described more fully hereinafter withreference to the accompanying drawings, in which exemplifyingembodiments are shown. The inventive concept may, however, be embodiedin many different forms and should not be construed as limited to theembodiments set forth herein; rather, these embodiments are provided byway of example so that this disclosure will be thorough and complete,and will fully convey the scope of the inventive concept to thoseskilled in the art. Like numbers refer to like elements throughout thedescription.

The term “proximal end” as used herein, when used in conjunction with acap assembly, refers to that end of the cap assembly which is farthestfrom the proximal end of the medicament delivery device, when the capassembly is properly mounted onto a medicament delivery device. Theproximal end of a medicament delivery device is that end which is to bepointed towards the injection site during medicament injection. The sameconsiderations also apply when referring to any component of the capassembly. The “distal end” is the opposite end relative to the proximalend. With “proximal direction” and, equivalently, “proximally” is meanta direction from the distal end towards the proximal end, along thecentral axis of the safety mechanism. With “distal direction” or“distally” is meant the opposite direction to “proximal direction”. Thesame definition also applies for the medicament container and anycomponent thereof.

The present disclosure relates to a cap assembly for a medicamentdelivery device. The cap assembly includes a cap and an elongatedsqueeze member. The cap is configured to be mounted to a proximal end ofa medicament delivery device, for example to the housing, or body, of amedicament delivery device. The cap has a tubular body which has adistal opening extending along the central axis of the tubular body.

The tubular body has a bottom structure which defines the proximal endwall of the distal opening. The bottom structure has a cam structure,provided inside the tubular body, in particular inside the distalopening. The tubular body has inner walls, i.e. the inner walls of thedistal opening provided with radial recesses.

The squeeze member is configured to be received by the tubular body, inparticular in the distal opening. The squeeze member has alongitudinally extending channel configured to receive a delivery membershield. The squeeze member furthermore has radial arms that are flexiblein the radial direction. The radial arms form part of a channel wall(s).The squeeze member furthermore has a proximal end face configured tocooperate with the cam structure of the cap. The squeeze member isconfigured to be axially displaceable from a first position in which theproximal end face bears against the cam structure to a second positionin which the squeeze member is received further by the cap. This axialdisplacement causes rotation of the squeeze member relative to the cap,and is obtained due to the cooperating proximal end face of the squeezemember and the cam structure of the cap.

The radial arms extend radially outside the outer surface of the squeezemember when the squeeze member is arranged in the first position. In thefirst position, each radial arm is received by a respective radialrecess of the tubular body. When the squeeze member is rotated, theradial arms disengage from the radial recesses, and as the squeezemember rotates so that the radial arms are moved in the circumferentialdirection away from their respective radial recess, the radial arms arepressed radially inwards by the inner walls of the tubular body. Thiscauses the radial arms to extend radially inwards of the inner surfaceof the channel of the squeeze member, reducing a cross-sectional area ofthe channel. The radial arms may thereby provide radial pressure onto adelivery member shield received by the squeeze member. The cap assemblycan thus engage with the delivery member shield such that when the capassembly is removed from a medicament delivery device, the deliverymember shield is removed simultaneously.

With reference to FIGS. 1-10 an example of a cap assembly will bedescribed. FIG. 1 shows a perspective view of a medicament deliverydevice 1, which in the present case may also be seen as a sub-assemblyof a medicament delivery device, because the depicted example does notcomprise an activation assembly, which is to be mounted to a distal endof the medicament delivery device 1.

The exemplified medicament delivery device 1 shown in FIG. 1 has aproximal end is and a distal end 1 b, and comprises a body, or housing,3, and a cap assembly 5.

Turning now to FIG. 2, an exploded view of the medicament deliverydevice 1 is shown. The medicament delivery device 1 comprises the capassembly 5, which comprises a cap 7 and a squeeze member 9, a medicamentcontainer assembly 11, which comprises the body 3 and a clamp member 13.The medicament delivery device 1 may further include a delivery membershield 15 and a medicament container 17 including a delivery member 19.

According to the example shown in FIG. 2, the medicament container 17 isa syringe and the delivery member 19 is a needle. Moreover, theexemplified the delivery member shield 15 includes a flexible innermember 15 a configured to receive the delivery member 19 and a rigidouter member 15 b configured to receive the flexible inner member 15 a.The rigid outer member 15 b has chamfered outer surfaces 15 c extendingparallel with each other in the longitudinal direction of the deliverymember shield 15. The exemplified delivery member shield 15 is a rigidneedle shield, but could alternatively be a flexible needle shield.

FIG. 3 shows a detailed view of the cap assembly 5. The exemplified cap7 has an outer body 7 a and an inner tubular body 7 b, coaxiallyarranged with the outer body. The tubular body 7 b has an axiallyextending distal opening 7 c. The tubular body 7 b is configured toreceive the squeeze member 9 in the distal opening 7 c.

The tubular body 7 b has a plurality of radial recesses 7 d. The radialrecesses 7 d extend in the longitudinal direction along a majority ofthe axial length of the tubular body 7 b, and thus of the distal opening7 c.

The squeeze member 9 is elongated and has a tubular shape. The squeezemember 9 has a channel 9 d extending in the longitudinal directionthrough the squeeze member 9, configured to receive the delivery membershield 15.

The squeeze member 9 furthermore has a proximal end face 9 a comprisinga plurality of elevated portions 9 b. Between each pair of adjacent pairof elevated portions 9 b is a cut-out 9 c with oppositely inclined orsloping surfaces. The proximal end face 9 a is hence provided with aplurality of teeth in the circumferential direction of the squeezemember 9, with a gradually increasing and decreasing elevation.

The squeeze member 9 comprises a plurality of radial arms 9 d which areflexible in the radial direction. The radial arms 9 d extend thecircumferential direction from the main body of the squeeze member 9 andhave an increasing thickness towards their end portions relative to thepoint of attachment to the main body of the squeeze member 9. Hereto,the end thickness of each radial arm is substantially thicker than thethickness of the channel wall.

The radial arms 9 e form part of the channel wall. The radial arms 9 eare by default configured to flex radially outwards from the outersurface of the squeeze member 9, as shown in FIG. 3. Hereto, the radialarms 9 e protrude radially from the outer surface of the main body ofthe squeeze member 9 when no external force is applied to the radialarms 9 e. The radial arms 9 e are configured to slide axially in arespective radial recess 7 d of the cap 7, when the squeeze member 9 ismoved linearly in the distal opening 7 c of the tubular body 7 b. Theradial recess 7 d have inclined surfaces in the circumferentialdirection, allowing the radial arms 9 e to disengage from the radialrecesses 7 d when the squeeze member 9 is rotated while being displacedin the distal opening 7 c, from a first position to a second position.The radial recesses 7 d and the radial arms 9 e may be seen to form aratchet configuration, with the radial arms 9 e being flexible radiallyinwards when the squeeze member 9 disengage from the radial recesses 7 dand the squeeze member 9 is being rotated.

According to the example shown in FIG. 3, the squeeze member 9 has aplurality of arms 9 e in a first radial plane along the axial directionof the squeeze member 9, and a plurality of radial arms 9 e in a secondplane axially spaced apart from the first plane. The exemplified squeezemember 9 hence has several layers of radial arms 9 e, in the axialdirection of the squeeze member 9.

FIG. 4 shows a top view of the cap 7, in particular seen from the distalend of the cap 7. The cap 7 has a bottom structure 7 e, which defines adistal end wall or surface of the distal opening 7 c. The bottomstructure 7 e has a cam structure 7 f, which according to the presentexample is annular in a radial plane. The cam structure 7 f isconfigured to cooperate with the proximal end face 9 a of the squeezemember 9.

FIG. 5 shows a longitudinal section of the cap 7. The cam structure 7 fhas a plurality of slanting surfaces, forming a gradually increasing anddecreasing teeth-like structure in the circumferential direction.Hereto, the cam structure 7 f has a plurality of elevated portions 7 g,of which one can be seen in FIG. 5, and cut-outs 7 h with oppositelyarranged inclined surfaces. Between each pair of adjacent elevatedportion 7 g, there is provided a cut-out 7 h. This configuration of thecam structure 7 f allows for cooperation with the correspondingstructure of the proximal end face 9 a of the squeeze member 9, as willbe described in more detail in the following.

FIG. 6 shows the squeeze member 9 arranged inside the tubular body 7 bof the cap 7. The squeeze member 9 is arranged in a first positionrelative to the cap 7. Here, the proximal end face 9 a of the squeezemember 9 bears against the cam structure 7 f arranged inside the tubularbody 7 b. Each elevated portion 9 b of the squeeze member 9 bearsagainst a respective top portion of the cut-out 7 h, closer to anelevated portion of the cam structure 7 f than to the lowest elevationalpoint of the cut-out 7 h.

As shown in the top view of FIG. 7, each radial arm 9 e of the squeezemember 9 is arranged in a respective radial recess 7 d of the innerwalls of the tubular body 7 b when the squeeze member 9 is in the firstposition.

FIG. 8 shows the squeeze member 9 in a second position. In the secondposition, the squeeze member 9 has been axially displaced relative tothe first position shown in FIG. 6. In particular, the squeeze member 9has been further received by the tubular body 7 b. Due to this proximaldisplacement of the squeeze member 9 the proximal end face 9 a and thecam structure 7 f have cooperated, causing the squeeze member 9 torotate relative to the cap 7. Hereto, the elevated portions 9 b of theproximal end face 9 a have slid down to the lowest elevational points ofthe cut-outs 7 h of the cam structure 7 f. Moreover, the elevatedportions 7 g of the cam structure 7 f have been fully received by thecut-out 9 c of the proximal end face 9 a of the squeeze member 9.

In FIG. 9, a top view of the situation shown in FIG. 8 is depicted. Theradial arms 9 e have disengaged from the radial recesses 7 d as thesqueeze member 9 is moved proximally from the first position to thesecond position, causing the squeeze member 9 to rotate, as indicated bythe arrows showing rotation. This causes the radial arms 9 e to bearagainst the inner walls of the tubular body 7 b, outside the radialrecesses 7 d, which are radially closer to the central axis of thetubular body 7 b. The radial arms 9 e are therefore pressed or flexedradially inwards. The radial arms 9 e have end portions that are thickerthan the wall thickness of the channel 9 d, and therefore, the radialarms 9 e are pressed into the channel 9 d, reducing the cross-sectionalarea of the channel 9 d. When the delivery member shield 15 is arrangedin the channel 9 d, the radial arms 9 e will engage with, or pressagainst, the outer surface of the delivery member shield 9 d.

FIG. 10 shows the medicament container assembly 11. It should be notedthat other medicament container assemblies than the one describedherebelow may be used in conjunction with the cap assembly 5 previouslydescribed. Similarly, the below described medicament container assembly11 may be used in conjunction with other cap assemblies than theexemplified cap assembly 5.

The exemplified medicament container assembly 11 includes the body 3 andthe clamp member 13.

The clamp member 13 is tubular and has a through-opening 13 a extendingin the longitudinal direction of the clamp member 13. The clamp member13 furthermore has a proximal end flange 13, or support surface,extending radially inwards.

The body 3 has an elongated shape and is configured to receive themedicament container 17. The body 3 has a proximal end 3 a and a distalend 3 b and a support structure 3 c arranged inside the body 3, closerto the proximal end 3 a than to the distal end 3 b. The supportstructure 3 c extends between opposite inner surfaces of the body 3. Thesupport structure 3 c is provided on, or attached to, the opposite innersurfaces of the body 3. The support structure 3 c has a central tubularportion 3 d provided with an axially extending through-opening 3 econfigured to receive the medicament container 17.

As shown in FIG. 1i , the body 3 furthermore has a radially flexiblefirst gripper arm 3 f and a radially flexible second gripper arm 3 garranged opposite relative to the first gripper arm 3 f. The firstgripper arm 3 f and the second gripper arm 3 g extend in the axialdirection of the body 3.

The first gripper arm 3 f and the second gripper arm 3 g are configuredto support a neck portion of the medicament container 17. According tothe example shown in FIG. 11, the first gripper arm 3 f and the secondgripper arm 3 g form part of the tubular portion 3 d.

The first gripper arm 3 f has a gripper portion 3 h provided at a distalend of the first gripper arm 3 f, extending radially inwards. The secondgripper arm 3 g has a gripper portion 3 i provided at a distal end ofthe second gripper arm 3 g, extending radially inwards.

The clamp member 13 is configured to receive the tubular portion 3 d ofthe body 3. In particular, the clamp member 13 is configured to bebrought around the tubular portion 3 d from the proximal end 3 a of thebody 3, and moved around the tubular portion 3 d such that the firstgripper arm 3 f and the second gripper arm 3 g are received by the clampmember 13 and pressed radially inwards by the inner surface of the clampmember 13. When the clamp member 13 has been set in its end positionduring assembly, the proximal end flange 13 b of the clamp member 13bears against the proximal end of the tubular portion 3 d.

With reference to FIGS. 12-15 methods of assembling a sub-assembly willnow be described.

FIG. 12 shows a longitudinal section of an example of a sub-assembly.Sub-assembly 21 includes the cap assembly 5 and the medicament containerassembly 11. FIG. 12 shows the sub-assembly 21 during assembly. Thesqueeze member 9 is in the first position inside the tubular body 7 b ofthe cap 7, and the delivery member shield 15 is arranged in the channelof the squeeze member 9. The medicament container 17 has been arrangedinside the body 3, and extends through the through-opening 3 e of thetubular portion 3 d, with a neck portion 17 a of the medicamentcontainer 17 extending proximally beyond the tubular portion 3 d. Thedelivery member 19 is arranged in the delivery member shield 15.

In FIG. 13, the sub-assembly 21 is shown in an assembled state. Thedistal end face of the squeeze member 9 was pushed towards the proximalend flange 13 b of the clamp member 13 as the cap assembly 5 and themedicament container assembly 11 were moved towards each other, causingthe squeeze member 9 to move from the first position to the secondposition, and thereby rotate due to the cooperation between the camstructure 7 f of the cap 7 and the proximal end face 9 a of the squeezemember 9. The radial arms 9 e of the squeeze member 9 have thus movedradially inwards as they were pressed towards the inner walls of thetubular body 7 b, outside the radial recesses 7 d, causing the radialarms 9 e to engage with the delivery member shield 15.

FIG. 14 shows a flowchart of a method of assembling a sub-assembly, forexample sub-assembly 21.

In a step a) the cap assembly 5 is provided.

In a step b), the squeeze member 9 is inserted into the distal opening 7c of the tubular body 7 b of the cap 7. The squeeze member 9 is movedtowards the bottom structure 7 e of the tubular body 7 b until theproximal end face 9 a of the squeeze member 9 contacts the bottomstructure 7 e, with each elevated portion 9 b of the squeeze member 9being arranged closer to an elevated portion 7 g of the cam structure 7f than to the lowest elevational point of the corresponding cut-outs 7 hof the cap 7. The squeeze member 9 is thus set in the first position.

In a step c) the cap 7 with the squeeze member 9 arranged therein isassembled with a medicament container assembly, for example medicamentcontainer assembly 11, including the medicament container 17 and thedelivery member shield 15.

In examples where the cap assembly 5 is assembled with the medicamentcontainer assembly 11, the distal end of the squeeze member 9 is pushedagainst the proximal end flange 13 b of the clamp member 13 providedaround the support structure 3 c of the body 3 and is moved in thedistal direction, causing the squeeze member 9 to move in the proximaldirection from the first position to the second position. Hence, duringthe assembly in step c), the squeeze member 9 is pushed further into thecap 7, moving from the first position to the second position, causingthe squeeze member 9 to rotate and grip the delivery member shield 15.

It should be noted that the cap assembly 5 could alternatively beassembled with another type of medicament container assembly, providedthat the medicament container assembly has a support surface againstwhich the distal end face of the squeeze member may be pushed duringassembly, to move the squeeze member from the first position to thesecond position.

The medicament container assembly 11 may be assembled according to themethod described by the flowchart in FIG. 15.

Hence, in a step A) the medicament container assembly 11 is provided.

In a step B) the medicament container 17 is inserted from a distal endopening of the body 3, with the delivery member 19 pointing in theproximal direction and the delivery member shield 15 being provided onthe delivery member 19.

The medicament container 17 is moved in the proximal direction until theneck portion 17 a of the medicament container 17 moves past the distalends of the first gripper arm 3 f and the second gripper arm 3 g, andthe delivery member shield 15 extends proximally through a proximalopening of the body 3.

In a step C) the clamp member 13 is moved over the delivery membershield 15, and into the body 3 through the proximal opening thereof.

In a step D) the clamp member 13 is moved in the distal direction overthe tubular portion 3 d, and thus over the first gripper arm 3 f and thesecond gripper arm 3 g. The first gripper arm 3 f and the second gripperarm 3 f are thereby bent or flexed radially inwards by the inner surfaceor wall of the clamp member 13.

In step D) the medicament container 17 may furthermore be pusheddistally until the clamp member 13 reaches an end position, i.e. whenthe proximal end flange 13 b bears against the proximal end of thetubular portion 3 d, and the first gripper arm 3 f and the secondgripper arm 3 g snap around the neck portion 17 a of the medicamentcontainer 17, thereby providing support of the neck portion 17 a.

In case that the cap assembly 5 is assembled with the exemplifiedmedicament container assembly 11 the steps a)-c) and steps A)-D) areinterconnected, in the sense that prior to step c) the medicamentcontainer assembly 11 has typically been assembled according to stepsA-C, while step D) and step c) may be carried out simultaneously. Thusin step D) the clamp member 13 may be pushed distally by the squeezemember 9 and the medicament container 17 and delivery member shield 15may be pushed distally by the cap 7, as the delivery member shield 15 isarranged in the squeeze member 9 and the cap 7 is moved distally towardsthe proximal end of the body 3.

With reference to FIGS. 16-28, another example of a cap assembly inaccordance with the present disclosure will be described. FIG. 16 showsa perspective view of a medicament delivery device 100, which in thepresent case may also be seen as a sub-assembly of a medicament deliverydevice, because the depicted example does not comprise an activationassembly, which is to be mounted to a distal end of the medicamentdelivery device 100. The example medicament delivery device 100 shown inFIG. 16 has a proximal end 101 a and a distal end 101 b, and comprises abody, or housing, 103, and a cap assembly 105. An activation assembly(not shown) may be mounted to the distal end 101 b.

Turning now to FIG. 17, an exploded view of the medicament deliverydevice 100 is shown. The medicament delivery device 100 comprises thecap assembly 105, which includes a cap 107, a spinner 108, a squeezer109, and a clamp 113. The medicament delivery device 100 furtherincludes a medicament container assembly 111 that includes body 103, adelivery member shield 115 and a medicament container 117 including adelivery member 119. According to the example shown in FIG. 17, themedicament container 117 is a syringe and the delivery member 119 is aneedle. Moreover, the example delivery member shield 115 includes aflexible inner member 115 a configured to receive the delivery member119 and a rigid outer member 115 b configured to receive the flexibleinner member 115 a. The rigid outer member 115 b has chamfered outersurfaces 115 c extending parallel with each other in the longitudinaldirection of the delivery member shield 115. Although the exampledelivery member shield 115 is a rigid needle shield, in other exampleembodiments, the delivery member shield 115 is a flexible needle shield.

FIG. 18 shows a detailed view of the cap 107. The cap 107 is configuredto be mounted to a proximal end of the medicament delivery device 100.The example cap 107 has a body 107 b that has an axially extendingdistal opening 107 c. The cap 107 is configured to receive the spinner108 in the distal opening 107 c. Further, the cap 107 has a proximal end107 e, and the proximal end 107 e has a cam surface 107 f. The camsurface 107 f is configured to cooperate with a proximal end face of thespinner 108. According to the present example, the cam surface 107 f isannular in a radial plane.

The cam surface 107 f has a plurality of slanting surfaces, forming agradually increasing and decreasing teeth-like structure in thecircumferential direction. Hereto, the cam surface 107 f has a pluralityof elevated portions 107 g and cut-outs 107 h with oppositely arrangedinclined surfaces. Between each pair of adjacent elevated portions 107g, there is provided a cut-out 107 h. This configuration of the camsurface 107 f allows for cooperation with the corresponding structure ofthe proximal end face of the spinner 108, as will be described in moredetail in the following.

FIG. 19 illustrates a detailed view of the squeezer 109. The squeezer109 is elongated and has a tubular shape. The squeezer 109 has a channel109 d extending in the longitudinal direction through the squeezer 109,and the channel 109 d is configured to receive the delivery membershield 115.

The squeezer 109 comprises a plurality of radial arms 109 e which areflexible in the radial direction. The radial arms 109 e extend from themain body 109 a of the squeezer 109 and have an increasing thicknesstowards their end portions 109 b relative to the point of attachment 109c to the main body 109 a of the squeezer 109. Hereto, the end thicknessof each radial arm 109 e is thicker than the thickness of the channelwall 109 i of the main body 109 a. In an example embodiment, thethickness of each radial arm 109 e is at least 5% thicker than thethickness of the channel wall 109 i. In another example, the thicknessof each radial arm 109 e is at least 10% thicker than the thickness ofthe channel wall 109 i. Other example thicknesses are possible as well.

As seen in FIG. 19, the radial arms 109 e form part of the channel wall109 i. The radial arms 109 e are by default configured to flex radiallyoutwards from the outer surface of the squeezer 109, as shown in FIG.19. Hereto, the radial arms 109 e protrude radially from the outersurface of the main body 109 a of the squeezer 109 when no externalforce is applied to the radial arms 109 e.

In an example embodiment, the squeezer 109 includes a plurality of setsof radial arms. For instance, as can be seen with reference to FIG. 19in combination with FIG. 28, the squeezer 109 has (i) a plurality ofarms 109 e in a first radial plane 109 f along the axial direction ofthe squeezer 109 and (ii) a plurality of radial arms 109 e in a secondplane 109 g axially spaced apart from the first plane. The examplesqueezer 109 hence has several layers of radial arms 109 e, in the axialdirection of the squeezer 109. Although this example shows two layers ofradial arms 109 e, in other example embodiments, more or fewer layers ofradial arms 19 e are possible. Further, although in the example of FIG.19 the radial arms 109 e are angled with respect to the radial planes109 f and 109 g, in other examples embodiments, the radial arms 109 eare parallel or substantially parallel to the radial planes 109 f and109 g.

FIG. 20 illustrates a detailed view of the spinner 108. In this exampleembodiment, the spinner 108 is elongated and has a tubular shape. Thespinner 108 has a body 108 e defining a longitudinally extending channel108 d configured to receive the squeezer 109. The spinner 108furthermore has a proximal end face 108 a configured to cooperate withthe cam surface 107 f of cap 107. In particular, the proximal end face108 a includes a plurality of elevated portions 108 b. Between each pairof adjacent pair of elevated portions 108 b is a cut-out 108 c withoppositely inclined or sloping surfaces. The proximal end face 108 a ishence provided with a plurality of teeth in the circumferentialdirection of the spinner 108, with a gradually increasing and decreasingelevation.

The spinner 108 also includes a plurality of holes 108 f in the body 108e that are configured to receive the plurality of radial arms 109 e ofthe squeezer 109 when the squeezer 109 is inserted into the spinner 108.In particular, when the squeezer 109 is inserted into the channel 108 d,the radial arms 109 e may deflect radially inward so that the squeezer109 is able to move through the channel 108 d. Further, when the radialarms 109 e align with the holes 108 f, the radial arms 109 e will flexoutward into the holes 108 f to return to their default position. Thisdefault position of the radial arms 109 e is shown in FIGS. 19 and 21.

During an assembly process of the medicament delivery device 100, axialdisplacement of the spinner 108 from (i) a first position in which theproximal end face 108 a bears against the cam surface 107 f and eachradial arm 109 e of the plurality of radial arms is positioned in arespective hole 108 f of the plurality of holes to (ii) a secondposition in which the spinner 108 is received further by the cap 107causes rotation of the spinner 108 relative to the cap 107 and thesqueezer 109. The rotation of the spinner 108 relative to the cap 107and the squeezer 109 causes the body 108 e of the spinner 108 to forceeach radial arm 109 e out of the respective hole 108 f and into thelongitudinally extending channel 109 d, so as to reduce across-sectional area of the longitudinally extending channel 109 d. Thisreduction of the cross-sectional area of the longitudinally extendingchannel 109 d allows the squeezer to securely grip or squeeze thedelivery member shield 115.

The axial displacement from the first position to the second positionduring the assembly process is described in greater detail withreference to FIGS. 21-24. FIG. 21 shows the spinner 108 arranged insidethe body 107 b of the cap 107. The spinner 108 is arranged in the firstposition relative to the cap 107. Here, the proximal end face 108 a ofthe spinner 108 bears against the cam surface 107 f arranged inside thebody 107 b. Each elevated portion 108 b of the spinner 108 bears againsta respective top portion of the cut-out 107 h, closer to an elevatedportion of the cam surface 107 f than to the lowest elevational point ofthe cut-out 107 h. As shown in the top view of FIG. 23, when the spinner108 is in this first position the radial arms 109 e are not yetextending 3 o into the channel 109 d. Rather, the radial arms 109 e arein their default position and are received by holes 108 f.

FIG. 22 shows the spinner 108 in the second position. In the secondposition, the spinner 108 has been axially displaced relative to thefirst position shown in FIG. 21. In particular, the spinner 108 has beenfurther received by the body 107 b. In an example embodiment, thisoccurs as the cap 107 is moved in distal direction 112 toward body 103.Due to this proximal displacement of the spinner 108, the proximal endface 108 a and the cam surface 107 f have cooperated, causing thespinner 108 to rotate relative to the cap 107 and the squeezer 109.Hereto, the elevated portions 108 b of the proximal end face 108 a haveslid down to the lowest elevational points of the cut-outs 107 h of thecam surface 107 f. Moreover, the elevated portions 107 g of the camsurface 107 f have been fully received by the cut-out 108 c of theproximal end face 108 a of the spinner 108.

This rotation of the spinner 108 relative to the cap 107 and thesqueezer 109 causes the body 108 e of the spinner 108 to force eachradial arm 109 e out of the respective hole and into the firstlongitudinally extending channel, so as to reduce a cross-sectional areaof the first longitudinally extending channel. In an example embodiment,during this rotation of the spinner 108 from the first position to thesecond position, the spinner 108 moves axially relative to the squeezer109.

In an example embodiment, the squeezer 109 is rotationally fixed to thecap 107. The squeezer 109 and the cap 107 may be rotationally fixed inany suitable manner. For instance, in the illustrated example, the cap107 includes protrusions 107 i (see FIG. 18) at the proximal end 107 e,and the squeezer 109 includes recesses or slits 109 h (see FIG. 19) atthe proximal end of the squeezer 109. During the assembly process, theprotrusions 107 i may be positioned in the slits 109 h so that thesqueezer 109 and the cap 107 are rotationally fixed to one another.

In FIG. 24, a top view of the situation shown in FIG. 22 is depicted. Asthe spinner 108 rotates, the holes 108 f move relative to the radialarms 109 e and the body 108 e of the spinner 108 engages the radial arms109 e. This engagement forces the radial arms 109 e to be pressed orflexed radially inwards. In the example shown, two radial arms 109 e arearranged opposite to each other in radial plane 109 f (see FIG. 19) ofthe squeezer, such that the two radial arms 109 e move towards eachother as the spinner 108 moves from the first position to the secondposition. Similarly, two radial arms 109 e are arranged opposite to eachother in radial plane 109 g (see FIG. 19) of the squeezer, such that thetwo radial arms move towards each other as the spinner 108 moves fromthe first position to the second position. Although the radial arms 109e in each radial plane 109 f, 109 g are spaced apart by approximately180 degrees, in other examples the radial arms 109 e may be spaced apartby a different number of degrees. Further, although each radial planeincludes two radial arms, each radial plane may include more or fewerradials arms.

As described above, the radial arms 109 e have end portions 109 b thatare thicker than the wall 109 i thickness of the channel 109 d, andtherefore, the radial arms 109 e are pressed into the channel 109 d,reducing the cross-sectional area of the channel 109 d. When thedelivery member shield 115 is arranged in the channel 109 d, the radialarms 109 e will engage with, or press against, the outer surface of thedelivery member shield 115. This engagement or pressing against createsa tight fit around the delivery member shield 115.

In an example embodiment, the cap assembly 105 also includes a clamp 113connected to the distal end of the squeezer 109. In particular, theclamp 113 is axially fixed to the distal end of the squeezer 109. Theclamp may help to secure the medicament container 117 when the capassembly 105 is assembled on the medicament container assembly 111. Withreference to FIGS. 25-28, the clamp 113 includes a main body 113 a. Inthis example, the main body 113 a is a tubular body and is configured tosurround the medicament container 117. The clamp 113 also includes aplurality of clamp arms 113 b flexible in a radial direction.

The clamp 113 is configured to interact with the body 103 of themedicament container assembly 111 in order to secure the medicamentcontainer 117 when the cap assembly 105 is assembled on the medicamentcontainer assembly 111. In particular, the body 103 of the medicamentcontainer assembly in includes an inner seat 121 through which themedicament container 117 extends, and clamp 113 is configured tointeract with this inner seat 121. As seen in FIG. 25, the inner seat121 is a support structure having a main body 121 a with a centraltubular portion 121 d provided with an axially extending through opening121 e configured to receive the medicament container 117. The centraltubular portion 121 d is also configured to receive the clamp 113 whenthe medicament container 117 is positioned in the inner seat 121.

During the assembly process, as cap 107 is moved in distal direction112, the clamp 113 is inserted into the inner seat 121. When the clamp113 is inserted into the inner seat 121, the clamp arms 113 b moveradially from an open position (see FIGS. 25 and 27) to a closedposition (see FIGS. 26 and 28). The central tubular portion 121 d forcesthe clamp arms 113 b to flex inwards as the clamp 113 moves in thedistal direction 112 into inner seat 121. When the clamp arms 113 b areflexed inward to the closed position, the clamp arms 113 b providesupport of a neck 123 (see FIG. 17) of the medicament container 117. Inparticular, when the clamp 113 is in its end position during assembly(see FIG. 28), the gripper portion 113 h (see FIGS. 27 and 28) of theclamp arms 113 b bear against the neck 123 of the medicament container117.

FIG. 29 illustrates an example method 200 of assembling a sub-assemblyfor a medicament delivery device. In an example embodiment, method 200can be carried out in a sub-assembly in accordance with the presentdisclosure, such as the sub-assembly of medicament delivery device 100.

The method includes, at block 202, providing a cap assembly. In anexample embodiment, the cap assembly is a cap assembly such as capassembly 105. The method further includes, at block 204, inserting thesqueezer 109 into the second longitudinally extending channel 108 d ofthe spinner 108. In an example embodiment, inserting the squeezer 109into the second longitudinally extending channel 108 d of the spinner108 involves inserting the squeezer 109 into the channel 108 d untileach radial arm 109 e of the squeezer 109 is received by a respectivehole 108 f of the spinner 108.

Still further, the method includes, at block 206, inserting the spinner108 into the cap 107 in a proximal direction and moving the spinner 108until the proximal end face 108 a of the spinner 108 contacts the camsurface 107 f to obtain the first position of the spinner 108. Themethod also includes, at block 208, assembling the cap 107 with thespinner 108 and squeezer 109 arranged therein with a medicamentcontainer assembly in comprising a delivery member shield 115 and asyringe 117, such that the squeezer 109 grips the delivery member shield115 and the clamp 113 grips a neck 123 of the syringe 117.

In an example embodiment of method 200 assembling the cap 107 with thespinner 108 and squeezer 109 arranged therein with the medicamentcontainer assembly 111 involves moving the spinner 108 axially relativeto the cap 107, so as to cause the spinner 108 to move proximally insidethe cap 107 from the first position to the second position. In anotherexample embodiment of method 200, the medicament delivery deviceincludes a body 103 surrounding the syringe 117 and comprising an innerseat 121 through which the syringe 117 extends. Further, assembling thecap 107 with the spinner 108 and squeezer 109 arranged therein with themedicament container assembly 111 involves inserting the clamp 113 intothe inner seat 121 such that the clamp arms 113 b move radially from theopen position to the closed position, so as to provide support of a neck123 of the syringe 117.

It should be understood that the illustrated components are intended asan example only. In other example embodiments, fewer components,additional components, and/or alternative components are possible aswell. Further, it should be understood that the above described andshown embodiments of the present disclosure are to be regarded asnon-limiting examples and that they can be modified within the scope ofthe claims.

While various aspects and embodiments have been disclosed herein, otheraspects and embodiments will be apparent to those skilled in the art.The various aspects and embodiments disclosed herein are for purposes ofillustration and are not intended to be limiting, with the true scopebeing indicated by the following claims, along with the full scope ofequivalents to which such claims are entitled. It is also to beunderstood that the terminology used herein is for the purpose ofdescribing particular embodiments only, and is not intended to belimiting.

1-20. (canceled)
 21. A cap assembly for a medicament delivery device,the cap assembly comprising: a cap configured to be mounted to aproximal end of the medicament delivery device, wherein the capcomprises a cam structure; a squeezer comprising (i) a body defining afirst longitudinally extending channel configured to receive a deliverymember shield and (ii) a plurality of radial arms flexible in a radialdirection; and a spinner comprising (i) a proximal end face configuredto cooperate with the cam structure of the cap, (ii) a body defining asecond longitudinally extending channel configured to receive thesqueezer, and (iii) a plurality of holes in the body of the spinnerconfigured to receive the plurality of radial arms of the squeezer. 22.The cap assembly of claim 21, wherein spinner is configured to moveaxially relative to the squeezer.
 23. The cap assembly of claim 21,wherein the cam structure comprises a plurality of elevated portionswith a cut-out having oppositely inclined surfaces provided between eachadjacent pair of elevated portions, in a circumferential direction ofthe cam structure.
 24. The cap assembly of claim 21, wherein theproximal end face of the spinner comprises a plurality of elevatedportions with a cut-out having oppositely inclined surfaces providedbetween each adjacent pair of elevated portions of the proximal endface, in a circumferential direction of the spinner.
 25. The capassembly of claim 21, wherein two of the radial arms are arranged in afirst radial plane of the squeezer, and wherein two other radial armsare arranged in a second radial plane axially spaced apart from thefirst radial plane.
 26. The cap assembly of claim 21, wherein eachradial arm has an increasing thickness in a direction from a point ofattachment of the radial arm towards an end portion of the radial arms,wherein the thickness of the end portion is thicker than a wallthickness of the body of the squeezer.
 27. The cap assembly of claim 21,wherein the cam structure is located on an inner surface of the cap. 28.The cap assembly of claim 21, wherein the delivery member shield is arigid needle shield or a flexible needle shield.
 29. The cap assembly ofclaim 21, wherein axial displacement of the spinner from (i) a firstposition in which the proximal end face bears against the cam structureand each radial arm of the plurality of radial arms is positioned in arespective hole of the plurality of holes to (ii) a second position inwhich the spinner is received further by the cap causes rotation of thespinner relative to the cap and the squeezer.
 30. The cap assembly ofclaim 29, wherein at least two of the radial arms are arranged oppositeto each other in a radial plane of the squeezer, such that the at leasttwo radial arms move towards each other as the spinner moves from thefirst position to the second position.
 31. The cap assembly of claim 29,wherein the rotation of the spinner relative to the cap and the squeezercauses the body of the spinner to force each radial arm out of therespective hole and into the first longitudinally extending channel, soas to reduce a cross-sectional area of the first longitudinallyextending channel.
 32. The cap assembly of claim 29, wherein theproximal end face of the spinner comprises a plurality of elevatedportions with a cut-out having oppositely inclined surfaces providedbetween each adjacent pair of elevated portions of the proximal endface, and wherein each elevated portion of the spinner is configured tobear against a region of a cut-out of the cam structure closer to anelevated portion of the cam structure than to a lowest elevational pointof the cut-out, in the first position of the spinner.
 33. The capassembly of claim 32, wherein the elevated portions of the spinner areconfigured to engage with the cut-outs of the cam structure in thesecond position of the spinner.
 34. A medicament delivery devicecomprising: a housing having a proximal opening; and the cap assembly ofclaim 21, wherein the cap assembly is configured to be mounted to themedicament delivery device to cover the proximal opening of the housing.35. The medicament delivery device of claim 34, wherein the medicamentdelivery device comprises a syringe and a housing surrounding thesyringe, the housing comprising an inner seat through which the syringeextends, the cap assembly further comprising: a clamp connected to adistal end of the squeezer, wherein the clamp comprises a plurality ofclamp arms flexible in a radial direction, wherein the clamp arms areconfigured to move radially from an open position to a closed positionwhen the clamp is inserted into the inner seat, so as to provide supportof a neck of the syringe.
 36. The medicament delivery device of claim34, wherein the medicament delivery device further comprises a syringe,wherein the housing of the medicament delivery device comprises an innerseat through which the syringe extends, wherein the cap assembly furthercomprises a clamp connected to a distal end of the squeezer, wherein theclamp comprises a plurality of clamp arms flexible in a radialdirection, and wherein the clamp arms move radially from an openposition to a closed position when the clamp is inserted into the innerseat, so as to support a neck of the syringe.
 37. A method of assemblinga sub-assembly for a medicament delivery device, the method comprising:providing a cap assembly as recited in claim 21; inserting the squeezerinto the second longitudinally extending channel of the spinner;inserting the spinner into the cap in a proximal direction and movingthe spinner until the proximal end face of the spinner contacts the camstructure; and assembling the cap with the spinner and squeezer arrangedtherein with a medicament container assembly comprising a deliverymember shield, such that the squeezer grips the delivery member shield.38. The method of claim 37, wherein assembling the cap with the spinnerand squeezer arranged therein with a medicament container assemblycomprising a delivery member shield and a syringe, such that thesqueezer grips the delivery member shield comprises: moving the spinneraxially relative to the cap from (i) a first position in which theproximal end face bears against the cam structure and each radial arm ofthe plurality of radial arms is positioned in a respective hole of theplurality of holes to (ii) a second position in which the spinner isreceived further by the cap causes rotation of the spinner relative tothe cap and the squeezer.
 39. The method of claim 38, wherein themedicament delivery device further comprises a housing surrounding asyringe and comprising an inner seat through which the syringe extends,wherein the medicament delivery device further comprises a clamp axiallyfixed to a distal end of the squeezer, wherein the clamp comprises aplurality of clamp arms flexible in a radial direction from an openposition to a closed position, and wherein the method further comprises:inserting the clamp into the inner seat such that the clamp arms moveradially from the open position to the closed position so as to providesupport of a neck of the syringe.
 40. The method of claim 37, whereininserting the squeezer into the second longitudinally extending channelof the spinner comprises inserting the squeezer into the secondlongitudinally extending channel until each radial arm of the squeezeris received by a respective hole in the body of the spinner.